I do not have a multicam but I used to run into issues when I accidentally switched to a different set of home coordinates - (my Centroid setup seems to have up to 5). When I did that, the spindle would crash the rack.
Anyhow I'll ask the questions that you'll need to answer to get help. Controller type, model, how far is it out of whack, is it one spot or many, etc?
They should be mapped out in a file maybe one per tool spot? That's is what you would need to revise but it sounds like a factory Rep course of help.
Good luck, and let us know some details.
GF