Going to need a bit more info on what your machine is, what gantry it has, what acceleration, what axis velocity, size of table.
What do you want to cut with it (material, minimum and maximum thicknesses). How much cutting to standing time are you expecting from your machine (is it a hobby environment or commercial production environment)
Kind of like asking can I make my car do 150mph, sure I can buy it may need a bigger engine, stronger gearbox, upgraded drivetrain, will it all fit, can I afford it, not got a clue,
Plasma is also really dirty.... Where do you think all that metal that gets blown out of the kerf goes? It's a good substitute for grinding paste... Hence ball screws may not last long in that environment
Rob