Which model of Taig is this? Is it a step/direction or phase drive? There might be a mechanical problem with your mill. It could have lubrication issues that were exacerbated by the long period of inactivity, as the oil hardened up with whatever gunk was in the slides. Do all the axes move freely by hand when the power's not on? Did you make a separate XML profile for the Mikini, or modify the one you were using for the Taig? Have you updated Mach3 recently? Is the computer the same one that's working on your other machine? Have you tried a fresh download of the Taig XML file? They can get corrupted. Have you bought it a new printer cable? It might have an intermittent flaw. (But make sure the one you get has continuity through all 25 pins).
There might be a problem with your drive that only can be fixed by sending it back to Taig (or troubleshooting it over the phone, which they do pretty well). But trying some simple stuff, like replacing cables, cleaning and relubing, readjusting the gibs, and reloading the software is a good place to start.