Only issues most users have is with ATI integrated graphics.
I suggest upgrading away from integrated graphics to any Nvidia card.
If you are going to be a "power" user on the laptop get a Quadro card and 4gb mem.
I have had no issues with either AMD or Core 2 duo.
I would use XPP but we will all inevitably need to change to Vista (or the next MS crap) at some point in time.