If you seal the openings around the fans you will likely succeed in making the room have slightly negative pressure in relationship to the outside as you have no means for air to enter the room. For air to flow you need both. 10 fans blowing 100 cfm should be plenty, that's 1 full air exchange a minute for a room 10x10x10. Have the air intake on the opposite side of the room from the fans. Disclaimer: assumes there is no combustion source in the area. Check OSHA for their recommendations on how many times per hour the air should be cycled. Every chemical has a different TLV, some chemicals are so bad you should not ever inhale any of them, cyanoacrylates , and epoxy catalysts are 2 examples as they release cyanide gas. I recommend a good organic vapor respirator if you must use VOCs in that area. Your health, Your family's health is too much to risk for the convienance of doing this indoors.