Making the domed shape on the top of the guitar would not be a problem but having to re-do the pockets for all your electronics will be. The holes for the knobs will have to be deepened from the back side and the pockets for th pick-ups will have to be filled to get them to the proper level. In addition I think the bridge will need to be changed the neck angle will need some attention.......hmmm this is sounding like a lot more work than I thought.
Is your neck a bolt on or is it glued in? There is a very logical reason I am asking this question!