Yep, regularly.
1. Design. Eagle, Altium aka Protel, Orcad, gEDA, whatever.
2. Laser print each layer to translucent "tracing" paper. Reverse the top layers before printing so the print ends up against the board.
3. Purchase pre-treated photosensitive board in single or double layer as appropriate.
4. Cut board to shape required, remove protective film, align and tape tracing paper to the board.
5. Place in an exposure box. These have three flouro UV tubes either side and, in the middle, a vacuum chamber with a plastic sheet top which sucks down and holds the paper firm against the PCB to keep the image sharp. Expose for the <trial and error time>, mine is about 80 seconds.
6. Pull the board out, remove the tracing paper, develop in Sodium Hydroxide (with gloves, tweezers) until the unwanted photoresist disappears. Rinse the board under the tap.
7. Etch the board in your choice of Ammonium Persulphate or Ferric Chloride. Both work better heated, even better still in a heated, agitated bubble tank - these are cheap.
8. Rinse again, use metho to wipe off the resist.
9. Drill.
10. Populate vias if you have any.
11. Populate the rest of the parts.
12. Spray with either copper lacquer from the hardware shop or a specific PCB lacquer from your local nerd shop.
Done.