You still need to think about the need for precision - precision costs money - and this should be your starting point. Like most engineering design a machine build pulls all the parameters in different directions and reaching a satisfactory - for you - compromise is what it is all about.
Precission has two main factors that impact on the choice of axis drive and these are loosley connected but need to be thought about. First is the repeatability of positioning - this is needed to cut complex curves and multiple cuts. Secondly is the need for absolute positioning of the tool so that parts can be made that will mate with other parts possibly bought in or made elsewhere.
What I am saying is that unless the sole object is to build the machine (and this is a worth while as a fun exercise) OR if you are serious about making stuff sort ot the accuracy requirements first in terms of tolerance and possitional repeatability of the stuff you want to make before even thinking about axis drives.
I wait with interest to see what you decide and others comments.