I would think so. But the Milltronics Centurions I used ran underneath in a DOS. Not Windows. (As I remember.) So you would have to find a USB DOS support. I have seen it on the internet. Anyway in Windows 98SE, every type of USB flash drive needs another different driver. Only Windows Me and up does not need the added drivers for USB flash drives.
One 64Mb flash drive holds as much as 88 3.5 floppys.