Every machine cuts differently, even from the same manufacturer. The best thing to do is just start experimenting. Start with 100% power and 100% speed and see what you get. If it's not deep enough then decrease the speed by 5% and see what you get. Rinse, lather and repeat.
Same thing with cutting, start out at 100% power and somewhere around 20% speed and decrease by 1% speed until you get the desired cut.
Once you get it all figured out, then you have to take into consideration the color of the acrylic, the temperature, humidity, etc. It's really not too difficult but can take a bit of time. Be sure to write everything down, I used a spreadsheet. The driver for my laser has a way to save profiles that hold the info for each material I vector/raster. I use that and back up the files very regularly.