Have you tried calling Predator or Bob for help???
A buddy of mine bought the Predator DNC package but never got it to work. We tried everything including Calling both Predator and Bob. No one could help.
I have a strange feeling that it has something to do with the Licensing through Bob.
Eventually my buddy got a refund for his Bob Software and switched to NC Plot for DNC.
I really don't know if there is any help for this but maybe. Keep trying.
BTW: What else have you tried besides the handshaking and what type of device are you using for the transfer, USB Adapter??
Have you adjusted the Baud, Parity, Com Port, and Stop Bits?