That's pretty friggin' expensive... and you'll not be able to use most G-code software as most run from a parallel port... You'd probably have to modify the controller to work. I'm not aware of any software that will work universally with serial controllers. Most serial systems are proprietary. It'd probably take a long time and a lot of unneccesary fiddling around to make them work.
I'd say that you'd be better off with a Xylotex board, set of Gecko drives or a Camtronics drive and a set of Nema32 motors. elsewhere. Either option is going to be hundreds less than those integrated items.