Bobcad is adding even more tutorials and FAQs on their support forum for V22.
This also includes info on Vista.
http://www.bobcad.com/support.html
Also one Vista issue that may cause problems due to adminstrator rights has to do with Vista login. This is not a Bobcad issue but could cause a problem running Bobcad or other programs that require hardware connections.
Make sure you set a password for logging into Vista. It does not matter if you are the only user. You can change the password back to a blank password in the same way you set one but you must initially set a password before Vista allows certain functions to run as an administrator. So if you have never set a password give it a try.