Since no one who knows what they are talking about has responded, I will try.
From what I can tell on the website, the Minitech driver-controller will take standard G and M codes which is what Mastercam and pretty much every other CAM application will output. That's the simplest take--often you will want to look at post-processors as well and there is a decent chance there are posts available for that mill. These are used to further tailor the CAM output for the specific mill they will be run on.
The minitech looks like a very nice machine but for $7500 new I'd rather buy two CNC'd Taig mills and then the kids can make twice as many chips
Other crazy idea is to find a local machine shop or manufacturer or college to help you out with all this. Machinists are becoming extremely hard to find due in large part to the fact that we keep trying to send boys to college for degrees they don't want rather than introducing them to skilled trades that they might really enjoy.