I'm not convinced that epoxy granite inside the SX2's column will do a lot for it stiffness wise. It should help a bit with dampening. The columns on these machines are simply to thin in cross section to effectively resist the machining forces involved here.
This is an interesting idea if I understand your intentions correctly. Alignment of the machine and maintaining that alignment while the epoxy is molded around it will be difficult. Do realize though that to do any good you will need a huge amount of Epoxy Granite.
Please post back with details on how these work out. The big problem for many of us though is getting such materials. Most of us strive to use easily obtained materials.
Interesting, never though about RTV as a mold release agent. Kooning that RTV comes in many grades which do you have experience with? I know of a few free flowing grade that might be good for coating molds.
Squaring everything up is important, there is plenty of info on the net for that. As others have mentioned though once you do this correcting for squareness becomes a much more involved project. You are basically left with hand scraping as your only option.
This leads me to the following advice, instead of modding this mill excessively, why not use the mill to build a purpose built
CNC epoxy granite machine? By doing so you can more easily work with the advantages of epoxy granite. There are some really interesting examples of such machines on the net. I've actually have worked on a few Epoxy Granite machines in the past that used the material as part of the machines frame with cast iron ways bolted in place. On these machines the chunks of the machine (epoxy granite blocks) where still bolted together. There are examples of epoxy granite machines molded as one piece of course but that implies an ability to handle and machine such beasts.
So in a nut shell I'd not rush into this project until a little more though is put into it. I'm certain that you could end up with a nice machine with a bit of thought. Most of that thought needs to go into how do you assemble and align the pieces of the machine.