I do not think pouring into the mould will work unless it is flat. Even with that you will have problems with air bubbles.
Nylon is not nice to work with. For the most part nylon is hydrous (it holds water). When you heat it it gives off water as steam and causes bubbling. This can be minimized by preheating the nylon prior to moulding.
Depending upon what you are moulding you will probably need to perform this as a injection mould, not a pour mould. Pouring is more for resins and liquid metal. You can not make plastic flow that easy without it cooling too fast and skinning over.
You need to review your design and determine what you need to do and what material you need.
Thermoplastics will flow around 320-375 degrees. Thermoset polymers (resin type, 2+ materials poured together) are a one shot deal that hardens/sets with time.
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