Anything with much over 4' of travel need something better than ACME screws. R&P is the only real solution for long lengths of travel. They can be a little less accurate over long distances depending on tolerance buildup. Software based error compensation can help with that. I think Mach3 has that capability.
From reading the Chinese spindle threads it appears that the Chinese spindles have documentation issues and many unhappy users. Until they get that sorted out I would recommend holding off on buying those. You need to be sure you can get three phase power at your location if you consider a spindle that needs it. Colombo seems to be the one to buy. I wouldn't buy one that has no warranty.
Joe's 4x4 builders seem to be really happy with their machines.
CarveOne
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CarveOne
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