Todd,
This sounds like a CNC Router, which I do not have much experience with. But doing a quick search on Google I found the company website:
ShopBot Tools, Inc
3333 Industrial Dr
Durham, NC 27704 USA
Phone: 919-680-4800; 888-680-4466
Fax: 919-680-4900
http://www.shopbottools.com
I am sure you can contact them on what is required to setup the router to communicate to a PC.
As for USB to serial adapters, you may have reliability issues that we have seen in the field. I recommend you find a PC with a standard builtin serial port from the motherboard or get some PCI serial card.
Good luck!
Greg Mercurio
Shop Floor Automations
www.cncnetworking.com